Ongoing Research

Project Title

IABC study - Predictors of neonatal and infant body composition and early infancy growth pattern and its effect on infant health in Jimma, Ethiopia

Principal investigator
Gregers Stig Andersen, PhD student

General Objective
To determine predictors of neonatal body composition and early infancy growth pattern and its effect on health during infancy

Specific objectives

  • To describe neonatal body composition
  • To identify predictors of neonatal body composition
  • To identify predictors -including birth weight of changes body composition from 0 to 6 months
  • To assess the relationship between birth weight and 6 month body composition
  • To assess the relationship between neonatal body composition and infant morbidity or mortality

Project Title:

Maternity study - Development of a strategy to improve the antenatal care (ANC) and delivery service in a low income setting - Experiences from Jimma town

Principal investigator

Sarah Fredsted Villadsen, PhD student

Objectives:

  • Improved quality of ANC and delivery service at health institutions (trainings of health staff, new equipment, laboratory facilities, adaption of WHO guideline for focused ANC) ANC)
  • Improved utilization of ANC and delivery service (community education, TBA involvement, improved service at the health facilities, and increased utilization)

Endpoint: Improved maternal and neonatal health

Project Title

SAM study - Severe acute malnutrition in children: body composition and linear growth during rehabilitation

Principal investigator

Tsinuel Girma, MD

Objectives:

  • To describe change in body composition of severely malnourished children before, during and after recovery
  • To describe body water changes in severely malnourished children before, during and after recovery

Project Title

ARTfood - The role of whey in nutritional support of HIV infected patients on antiretroviral treatment: A randomized trial in Jimma, Ethiopia

Principal investigator

Kim Fleischer Michaelsen

Objectives:

General objective
To assess the effect of a whey-containing nutritional supplement to HIV infected patients commencing antiretroviral treatment (ART) on general and HIV-specific treatment outcomes

Specific objectives

Primary outcomes

  • To assess the effect of a whey-containing nutritional supplement, and the timing of such a supplement, on lean body mass, grip strength and physical activity

Secondary outcomes

  • To assess the effect of a whey-containing nutritional supplement on IGF-1
  • To assess the effect of a whey-containing nutritional supplement on quality of life
  • To assess the effect of a whey-containing nutritional supplement on viral load, CD4 count, and adherence to ART
  • To assess the effect of whey, nutritional intervention on: Nevirapine and Efavirenze drug level in an HIV population initiating treatment
  • To identify the predictors and causes of mortality in the first year of ART initiation

Study progress

The study recruits HIV patients at the time of ART initiation from HIV clinics of a teaching hospital and two local primary care centres. The HIV patients are randomized to take nutritional supplement for the first three months and are followed up for twelve months. By April 2012, 280 study participants were enrolled in the study and the recruitment is expected to continue until August 2012.